Spinal pain is a very common disorder in the clinical practice and an important cause of man-power loss. Radiological investigations are commonly used to identify the underlying pathology of spinal pain. Along with the technological advancements, the radiological techniques have improved a lot during the last few decades. This review explains the use, advantages and restrictions of direct roentgenogram, myelograpy applications, computed tomography, magnetic resonance imaging, discography and spinal angiography which are commonly used radiological techniques in the diagnosis and follow-up of spinal pain conditions. Better understanding of the indications, advantages and disadvantages of such radiological techniques by the clinicians will improve the clinical output while optimizing the problems such as x-ray exposure and economical burden.