The Official Journal of the Turkish Society of Algology
ISSN 1300-0012 E-ISSN 2458-9446

Sandeep Diwan1, Anju Gupta2

1Department of Anaesthesiology and Critical Care, Sancheti Hospital, Pune, India
2Department of Anesthesia, Pain Medicine and Critical Care, AIIMS, New Delhi, India

We express our sincere gratitude to the authors for their interest in our article titled “Percutaneous Pulsed Radiofrequency Ablation of Articular Nerves of the Hip Joint in Patients with Chronic Hip Pain Refractory to Conventional Analgesics”[1] and value the opportunity to elucidate several significant points mentioned in their correspondence.

Initially, we concur that the nomenclature related to radiofrequency (RF) techniques has been historically inconsistent in the literature. Pulsed radiofrequency (PRF) is mechanistically distinct from traditional continuous radiofrequency neurotomy, especially concerning tissue temperature and the lack of pronounced thermocoagulative lesions. Nonetheless, the phrase “pulsed radiofrequency ablation” has been inconsistently employed in pain literature since its inception in clinical practice until the recent times. It is generally referred to as radiofrequency therapies aimed at neural targets, despite the lack of true destructive neurolysis.[2,3] We recognize that the language may lack semantic precision, and that “pulsed radiofrequency treatment” or “pulsed radiofrequency neuromodulation” would offer a more technically accurate description. We commend the authors for emphasizing this distinction. Importantly, despite increasing use of pulsed radiofrequency interventions (PRF, pulsed RF, PRF lesioning, PRF ablation, RF denervation, RF neurotomy, RF lesioning, RF neuromodulation), at least, we are unaware of an universally accepted Delphi-based consensus nomenclature defining the terminology of PRF versus ablative RF techniques.

All patients in the study had chronic refractory hip pain and were undergoing multimodal pharmacological care prior to referral for interventional treatment about the use of pregabalin. Pregabalin was not given as a study-specific intervention; instead, it was a component of the baseline conservative analgesic regimen indicated before contemplating operative therapy (often prescribed by the surgeons). Given that all patients were administered a similar baseline analgesic regimen, we do not consider this to have created a differential impact on treatment outcomes. Importantly, our study reflects a real-world clinical practice model in a high-volume orthopedic referral center, where interventional pain procedures are commonly integrated with ongoing pharmacological therapy rather than preceded by complete withdrawal of existing analgesics. The sudden cessation of chronic pain medications exclusively for procedure assessment may not always be practical or ethically justifiable in patients experiencing extreme refractory pain.[3] We recognize that the justification for referencing these medications may have been articulated more clearly in the manuscript to eliminate uncertainty.

We express our gratitude to the writers for meticulously evaluating the procedural statistics. The observation about Figure 1b is duly noted. The fluoroscopic image seems more medial than the textual description indicates, possibly due to projection orientation and fluoroscopic angulation during image acquisition, rather than an intentional mismatch in target position. The procedural strategy was primarily based on the notion that nociceptive innervation of the anterior hip capsule is distributed over the capsular brim in both medial and lateral regions rather than confined to a single fluoroscopic spot.[4] The targeting approach therefore intentionally sought coverage across the anterior capsular articular territory, including femoral and obturator articular contributions, which may variably project on two-dimensional fluoroscopic imaging.[5,6] Consequently, isolated interpretation of static fluoroscopic needle position may oversimplify the procedural rationale without considering the underlying three-dimensional capsular anatomy.[7,8] We concur that enhanced radiological clarity and labelling would have augmented reproducibility for readers endeavouring to execute the process. We value this insightful remark and concur that enhanced figure representation is consistently preferable in image-guided intervention literature.

Finally, we are encouraged that the correspondence has stimulated detailed technical discussion regarding hip articular branch interventions. Such exchanges are valuable because they remind all of us that, in pain medicine, terminology, anatomy, and fluoroscopic interpretation often generate nearly as much debate as the intervention itself.

We thank the authors once again for their thoughtful comments and for their contribution to advancing discussion in this evolving field.

Cite this article as: Diwan S, Gupta A. Response to Letter to the Editor: Percutaneous pulsed radiofrequency ablation of articular nerves of the hip joint in patients with chronic hip pain refractory to conventional analgesics. Agri 2026;38(3):212-213. doi: 10.5606/agri.2026.6388.

Author Contributions

All authors contributed equally to this article.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Use for AI for Writing Assistance

The authors declare that artificial intelligence (AI) tools were not used, or were used solely for language editing, and had no role in data analysis, interpretation, or the formulation of conclusions. All scientific content, data interpretation, and conclusions are the sole responsibility of the authors. The authors further confirm that AI tools were not used to generate, fabricate, or ‘hallucinate’ references, and that all references have been carefully verified for accuracy.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.

Data Sharing Statement
The data that support the findings of this study are available from the corresponding author upon reasonable request.

References

  1. Diwan S, Gupta A, Sancheti P, Sanghvi S, Panchawagh S. Percutaneous pulsed radiofrequency ablation of articular nerves of the hip joint in patients with chronic hip pain refractory to conventional analgesics. Agri 2024;36:83-91. doi: 10.14744/agri.2023.90236.
  2. Bogduk N. Pulsed radiofrequency. Pain Med 2006;7:396-407. doi: 10.1111/j.1526-4637.2006.00210.x.
  3. Shane A, Bailey S. Radiofrequency ablation for chronic knee, hip, and shoulder pain: CADTH Health Technology Review [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK598215/ [Accessed: May 07, 2026]
  4. Ruiz Ibán MÁ, Oteo-Álvaro Á, Miguéns Vázquez X, Ávila JL, Ribera H, Pérez-Páramo M. Efficacy and safety of pregabalin for postoperative pain after total hip and knee arthroplasty: a systematic review and meta-analysis. J Orthop Surg Res 2025;20:261. doi: 10.1186/s13018-025-05675-6.
  5. Pun M, Ng T, Vermeylen K, Tran J. Innervation of the hip joint: implications for regional anaesthesia and image-guided interventional pain procedures. BJA Educ 2024;24:191-202. doi: 10.1016/j. bjae.2024.02.005.
  6. Şencan S, Saçaklıdır R, Gündüz OH. Fluoroscopy-guided triple hip block for patients with hip osteoarthritis: A new approach. Agri 2024;36:120-2. doi: 10.14744/agri.2022.26878.
  7. Laumonerie P, Dalmas Y, Tibbo ME, Robert S, Durant T, Caste T, et al. Sensory Innervation of the Hip Joint and Referred Pain: A Systematic Review of the Literature. Pain Med 2021;22:1149-1157. doi: 10.1093/pm/pnab061.
  8. Short AJ, Barnett JJG, Gofeld M, Baig E, Lam K, Agur AMR, et al. Anatomic Study of Innervation of the Anterior Hip Capsule: Implication for Image-Guided Intervention. Reg Anesth Pain Med 2018;43:186-192. doi: 10.1097/AAP.0000000000000701.