The comparison of bupivacaine, tramadol and their combination for postoperative analgesia of laparoscopic cases
G. Arıcı1, T. Aydoğdu2, N Şahin3, M. Erman4
1Akdeniz Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Araş. Görevlisi
2Akdeniz Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Doç. Dr.
3Akdeniz Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Yrd. Doç. Dr.
4Akdeniz Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Prof. Dr.
Keywords: Tramadol, postoperative analgesia
Abstract
The purpose of this study was to compare the efficacy of tramadol (T), which is a centrally effective analgesic, and bupivacaine (B), in a double-blind, randomized study of 57 female patients with a median age of 30.17 ± 7.21 after laparoscopic gynecologic surgery. Patients were allocated randomly to one of the five groups and recieved 10 ml of: I. saline (n=12), II. 100 mg tramadol (n=12), III. 100 mg tramadol in 0.5 % bupivacaine with epinephrine (1/200.000) (n=11), IV. 0.5 % bupivacaine with epinephrine (1/200.000) (n=11) injected into the mesosalpinx. In the fifth group (n=11) 100 mg tramadol was administered intravenously at the end of the operation. Each patient was asked to degree her pain via 100 mm Visuel Analogue Scale, 30 minutes, 3, 6, 24 hours after the end of the operation. The time and amount of analgesic drug, complications, the time needed to return to normal activities were noted. The best postoperative analgesia was observed in the third group.